Title : IL-22 alleviates the fibrosis of hepatic stellate cells via the inactivation of NLRP3 inflammasome signaling.

Pub. Date : 2021 Oct

PMID : 34447480






2 Functional Relationships(s)
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1 Following addition of Nigericin, a NLRP3 activator, the levels of oxidative stress and fibrosis were measured. Nigericin NLR family pyrin domain containing 3 Homo sapiens
2 However, the NLRP3 activator Nigericin reversed the inhibitory effects of IL-22 on the induction of oxidative stress and fibrosis of HSCs induced by TGF-beta. Nigericin NLR family pyrin domain containing 3 Homo sapiens