Pub. Date : 2021 Aug 23
PMID : 34445767
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Suppression of LPS-Induced Inflammation and Cell Migration by Azelastine through Inhibition of JNK/NF-kappaB Pathway in BV2 Microglial Cells. | azelastine | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Furthermore, Aze inhibited LPS-induced IkappaB phosphorylation, thereby suppressing nuclear translocation of NF-kappaB. | azelastine | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Collectively, our data demonstrate that Aze exerts anti-inflammatory and anti-migratory effects through inhibition of the JNK/NF-kappaB pathway in BV2 cells. | azelastine | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |