Title : Propranolol inhibits infantile hemangioma by regulating the miR-424/vascular endothelial growth factor-A (VEGFA) axis.

Pub. Date : 2021 Jul

PMID : 34430434






5 Functional Relationships(s)
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1 Propranolol inhibits infantile hemangioma by regulating the miR-424/vascular endothelial growth factor-A (VEGFA) axis. Propranolol vascular endothelial growth factor A Homo sapiens
2 As the concentration of propranolol increased, XPTS-1 cell viability gradually decreased (P<0.05), and the expression level of VEGFA decreased (P<0.05). Propranolol vascular endothelial growth factor A Homo sapiens
3 Compared with the propranolol group, the XPTS-1 cell viability and invasion ability in the propranolol + VEGFA-si group were significantly decreased (P<0.05), while the level of apoptosis increased (P<0.05). Propranolol vascular endothelial growth factor A Homo sapiens
4 Compared with the propranolol group, the XPTS-1 cell viability and invasion ability in the propranolol + VEGFA-si group were significantly decreased (P<0.05), while the level of apoptosis increased (P<0.05). Propranolol vascular endothelial growth factor A Homo sapiens
5 Conclusions: Propranolol affects the malignant biological behavior of IHA cells by regulating the miR-424/VEGFA axis. Propranolol vascular endothelial growth factor A Homo sapiens