Title : Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.

Pub. Date : 2021 Aug 20

PMID : 34416891






1 Functional Relationships(s)
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1 We found that treatment with valproate improved the swimming of the MJD zebrafish, affected levels of acetylated histones 3 and 4, but also increased expression of polyglutamine expanded human ataxin-3. polyglutamine ataxin 3 Homo sapiens