Title : Intravenous administration of Tat-NR2B9c peptide, a PSD95 inhibitor, attenuates reinstatement of cocaine-seeking behavior in rats.

Pub. Date : 2022 Jan 7

PMID : 34416299






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Intravenous administration of Tat-NR2B9c peptide, a PSD95 inhibitor, attenuates reinstatement of cocaine-seeking behavior in rats. Cocaine tyrosine aminotransferase Rattus norvegicus
2 We found that Tat-NR2B9c, administered intravenously, attenuated the reinstatement of active lever presses induced by a priming dose of cocaine or by drug-associated conditioned stimuli. Cocaine tyrosine aminotransferase Rattus norvegicus
3 At the same time, the GluN2B/PSD95 complex levels were decreased in the ventral hippocampus of rats that previously self-administered cocaine injected with Tat-NR2B9c during cocaine- or cue-induced reinstatement. Cocaine tyrosine aminotransferase Rattus norvegicus
4 At the same time, the GluN2B/PSD95 complex levels were decreased in the ventral hippocampus of rats that previously self-administered cocaine injected with Tat-NR2B9c during cocaine- or cue-induced reinstatement. Cocaine tyrosine aminotransferase Rattus norvegicus