Title : [The effect of glucocorticoids in combination with azithromycin or theophylline on cytokine production by NK and NKT-like blood cells of patients with chronic obstructive pulmonary disease].

Pub. Date : 2021 Jul

PMID : 34414894






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Budesonide reduced synthesis of interleukin 4 (IL-4), CXCL8, tumor necrosis factor alpha (TNFalpha) by NK and NKT-like cells, as well as production of interferon gamma (IFNgamma) by NK cells. Budesonide C-X-C motif chemokine ligand 8 Homo sapiens
2 The combination of azithromycin and budesonide had a more pronounced inhibitory effect on the production of IL-4 and CXCL8 by NK and NKT-like cells than the effect of these drugs alone. Budesonide C-X-C motif chemokine ligand 8 Homo sapiens
3 The combination of theophylline and budesonide suppressed synthesis of IL-4 and CXCL8 by NK and NKT-like cells, as well as the production of TNFalpha and IFNgamma by NK cells stronger than budesonide alone. Budesonide C-X-C motif chemokine ligand 8 Homo sapiens