Title : RARγ activation sensitizes human myeloma cells to carfilzomib treatment through the OAS-RNase L innate immune pathway.

Pub. Date : 2022 Jan 6

PMID : 34411225






1 Functional Relationships(s)
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1 Similar to ATRA, BMS961, a selective RARgamma agonist, could also (re)sensitize MM cells to Cfz in vitro, and both ATRA and BMS961 significantly enhanced the therapeutic effects of Cfz in established MM in vivo. Tretinoin retinoic acid receptor gamma Homo sapiens