Title : Amyloid-β induced membrane damage instigates tunneling nanotube-like conduits by p21-activated kinase dependent actin remodulation.

Pub. Date : 2021 Dec 1

PMID : 34403739






2 Functional Relationships(s)
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1 Moreover, the formation of TNT-like conduits was inhibited by preventing PAK1-dependent internalization of oAbeta using the small-molecule inhibitor IPA-3, a highly selective cell-permeable auto-regulatory inhibitor of PAK1. 1-isopropyldiazen-1-ium-1,2-diolate p21 (RAC1) activated kinase 1 Homo sapiens
2 Moreover, the formation of TNT-like conduits was inhibited by preventing PAK1-dependent internalization of oAbeta using the small-molecule inhibitor IPA-3, a highly selective cell-permeable auto-regulatory inhibitor of PAK1. 1-isopropyldiazen-1-ium-1,2-diolate p21 (RAC1) activated kinase 1 Homo sapiens