Pub. Date : 2021 Oct 15
PMID : 34400180
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G. | Cyclic AMP | protein kinase cGMP-dependent 1 | Homo sapiens |
| 2 | However, the contributions of the two substituents that differentiate cGMP from cAMP (i.e. 6-oxo and 2-NH2) to the cGMP-versus-cAMP selectivity of PKG remain unclear. | Cyclic AMP | protein kinase cGMP-dependent 1 | Homo sapiens |
| 3 | However, the contributions of the two substituents that differentiate cGMP from cAMP (i.e. 6-oxo and 2-NH2) to the cGMP-versus-cAMP selectivity of PKG remain unclear. | Cyclic AMP | protein kinase cGMP-dependent 1 | Homo sapiens |
| 4 | Therefore, understanding the conformational dynamics of both the protein and ligand is essential to explain the cGMP-versus-cAMP selectivity of PKG. | Cyclic AMP | protein kinase cGMP-dependent 1 | Homo sapiens |