Title : Lactic acid in tumor invasion.

Pub. Date : 2021 Nov

PMID : 34400170






1 Functional Relationships(s)
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1 A growing number of studies have demonstrated that lactic acid regulates the degradation of collagen IV, collagen VII, and glycoprotein; the synthesis of collagen I; and multiple signaling pathways, including TGF-beta/Smad, Wnt/beta-catenin, IL-6/STAT3, and HGF/MET, which are associated with basement membrane (BM) remodeling and epithelial-mesenchymal transition (EMT), two hallmarks of the tumor invasive process. Lactic Acid interleukin 6 Homo sapiens