Title : Development of 2D, 3D-QSAR and Pharmacophore Modeling of Chalcones for the Inhibition of Monoamine Oxidase B.

Pub. Date : 2021 Aug 16

PMID : 34397324






2 Functional Relationships(s)
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1 Several functionalized chalcone derivatives were shown to have potential reversible MAO-B inhibitory activity, which have recently been reported from our laboratory. Chalcone monoamine oxidase B Homo sapiens
2 METHODS: With the experimental results of about 70 chalcone derivatives, we further developed a pharmacophore modelling, and 2D and 3D- QSAR analyses of these reported chalcones for MAO-B inhibition. Chalcone monoamine oxidase B Homo sapiens