Pub. Date : 2021 Nov
PMID : 34397117
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood. | polyglutamine | ataxin 3 | Homo sapiens |
| 2 | RESULTS: Statistical analyses revealed a correlation with clinical parameters and a stability of polyQ-expanded ataxin-3 during conversion from the pre-ataxic to the ataxic phases. | polyglutamine | ataxin 3 | Homo sapiens |
| 3 | CONCLUSIONS: The novel immunoassay is able to quantify polyQ-expanded ataxin-3 in plasma and CSF, whereas ataxin-3 levels in plasma correlate with disease severity. | polyglutamine | ataxin 3 | Homo sapiens |
| 4 | Longitudinal analyses demonstrated a high stability of polyQ-expanded ataxin-3 over a short period. | polyglutamine | ataxin 3 | Homo sapiens |