Title : AURKB promotes tumorigenesis and carboplatin resistance by regulating the ERK pathway in neuroblastoma cells.

Pub. Date : 2021 Aug 16

PMID : 34396896






1 Functional Relationships(s)
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1 Additionally, AURKB overexpression could potentiate the invasion and the expression of MRP1 and Ki67, while suppresses apoptosis in SK-N-AS-R and IMR-32-R, whereas ERK inhibitor U0126 could reverse the phenomenon caused by AURKB overexpression.Conclusion: AURKB overexpression was strongly associated with poor prognosis and carboplatin resistant acquisition. U 0126 mitogen-activated protein kinase 1 Homo sapiens