Pub. Date : 2021
PMID : 34394836
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Leonurine Ameliorates Oxidative Stress and Insufficient Angiogenesis by Regulating the PI3K/Akt-eNOS Signaling Pathway in H2O2-Induced HUVECs. | leonurine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | At the same time, LEO treatment significantly promoted the phosphorylation level of angiogenic protein PI3K, Akt, and eNOS and the expression level of survival factor Bcl2 and decreased the expression level of death factor Bax and caspase3. | leonurine | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In conclusion, our findings suggested that LEO can ameliorate the oxidative stress damage and insufficient angiogenesis of HUVECs induced by H2O2 through activating the PI3K/Akt-eNOS signaling pathway. | leonurine | AKT serine/threonine kinase 1 | Homo sapiens |