Title : Amplification by tramadol of PGD2-induced osteoprotegerin synthesis in osteoblasts: Involvement of μ-opioid receptor and 5-HT transporter.

Pub. Date : 2021 Sep

PMID : 34392133






1 Functional Relationships(s)
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1 Not the selective norepinephrine reuptake inhibitor reboxetine but the selective serotonin reuptake inhibitors fluvoxamine and sertraline upregulated the PGD2-induced osteoprotegerin release, which was further amplified by morphine. Fluvoxamine tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus