Title : A three-pocket model for substrate coordination and selectivity by the nucleotide sugar transporters SLC35A1 and SLC35A2.

Pub. Date : 2021 Sep

PMID : 34384782






2 Functional Relationships(s)
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1 Furthermore, Q129 and Q278 of SLC35A2 in the middle pocket appear to interact specifically with the beta-phosphate of UDP while the corresponding A105 and A253 residues in SLC35A1 do not interact with CMP, which lacks a beta-phosphate. beta-phosphate solute carrier family 35 member A2 Homo sapiens
2 Furthermore, Q129 and Q278 of SLC35A2 in the middle pocket appear to interact specifically with the beta-phosphate of UDP while the corresponding A105 and A253 residues in SLC35A1 do not interact with CMP, which lacks a beta-phosphate. beta-phosphate solute carrier family 35 member A2 Homo sapiens