Title : [The effects of shikonin on liver cancer cells SMMC-7721 apoptosis and its mechanism].

Pub. Date : 2021 Jul

PMID : 34374263






1 Functional Relationships(s)
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1 Results: In vitro experiments, shikonin could inhibit the proliferation of SMMC-7721 cells and induce their apoptosis(P<0.01), up-regulate the expression of p53 gene, down-regulate the phosphorylation levels of AKT and PI3K protein. shikonin tumor protein p53 Homo sapiens