Title : Chondrocyte Tsc1 controls cranial base bone development by restraining the premature differentiation of synchondroses.

Pub. Date : 2021 Dec

PMID : 34365025






2 Functional Relationships(s)
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1 Herein, we report that constitutive activation of the mechanistic target of rapamycin complex 1 (mTORC1) signaling via Tsc1 (Tuberous sclerosis 1) deletion in chondrocytes causes abnormal skull development with decreased size and rounded shape. Sirolimus TSC complex subunit 1 Mus musculus
2 Herein, we report that constitutive activation of the mechanistic target of rapamycin complex 1 (mTORC1) signaling via Tsc1 (Tuberous sclerosis 1) deletion in chondrocytes causes abnormal skull development with decreased size and rounded shape. Sirolimus TSC complex subunit 1 Mus musculus