Title : [Effect of FLT3-ITD Length on 32D Cell Proliferation, Apoptosis and Sensitivity to FLT3 Inhibitor].

Pub. Date : 2021 Aug

PMID : 34362479






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Under the exposure of FLT3 inhibitor AC220, the IC50 values was 0.183, 0.446 and 0.836 nmol/L, and apoptosis rates was 88.6%, 34.2% and 16.1%, respectively. quizartinib FMS-like tyrosine kinase 3 Mus musculus
2 CONCLUSION: FLT3-ITD mutant expressed cell strains with longer ITD show higher capacity of proliferation and higher tolerance to AC220 treatment. quizartinib FMS-like tyrosine kinase 3 Mus musculus