Title : Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome.

Pub. Date : 2021 Aug 6

PMID : 34355696






2 Functional Relationships(s)
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1 The drugs targeting these three proteins (Pacritinib, DMF, and EPO) were able to rescue different phenotypes of MECP2 inactivation in cultured human neural cell types, and appeared to converge on Nuclear Factor Kappa B (NF-kappaB) signaling in inflammation. Dimethylformamide nuclear factor kappa B subunit 1 Homo sapiens
2 The drugs targeting these three proteins (Pacritinib, DMF, and EPO) were able to rescue different phenotypes of MECP2 inactivation in cultured human neural cell types, and appeared to converge on Nuclear Factor Kappa B (NF-kappaB) signaling in inflammation. Dimethylformamide nuclear factor kappa B subunit 1 Homo sapiens