Title : Cyclin-dependent kinase inhibitor 1B acts as a novel molecule to mediate testosterone synthesis and secretion in mouse Leydig cells by luteinizing hormone (LH) signaling pathway.

Pub. Date : 2021 Aug

PMID : 34355300






1 Functional Relationships(s)
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1 These findings indicate that p27 plays vital roles in LH-induced testosterone production, providing a novel mechanism that p27 acts as an upstream molecule to elevate ERK1/2 phosphorylation to promote the expression of StAR and other cholesterol-metabolizing enzymes. Cholesterol mitogen-activated protein kinase 3 Mus musculus