Title : Early conformational changes and activity modulation induced by guanidinium chloride on intestinal alkaline phosphatase.

Pub. Date : 1987 Dec 1

PMID : 3435466






1 Functional Relationships(s)
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1 Moderate concentrations of guanidinium chloride induce both instantaneous and time-dependent modifications of the catalytic and optical properties of intestinal alkaline phosphatase, which undergoes consecutive conformational transitions at about 0.05 M, 0.25 M and 1.0 M denaturant. denaturant alkaline phosphatase, intestinal Homo sapiens