Title : Andrographolide, a novel inducer of apelin gene expression.

Pub. Date : 2021 Nov 15

PMID : 34352330






4 Functional Relationships(s)
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1 Andrographolide, a novel inducer of apelin gene expression. andrographolide apelin Rattus norvegicus
2 AIMS OF THE STUDY: This study sought to investigate the effect of Andrographolide on apelin gene expression and serum levels of glucose. andrographolide apelin Rattus norvegicus
3 RESULTS: The results of this study revealed that 3.5 and 7 mg doses per kg of body weight of andrographolide, for six days, significantly increased hepatic expression of apelin gene in male Wistar rats, as compared with the control group (p < 0.05). andrographolide apelin Rattus norvegicus
4 CONCLUSIONS: Our results suggest that Andrographolide can elicit an increase of hepatic apelin gene expression and a decrease in serum levels of blood glucose. andrographolide apelin Rattus norvegicus