Title : Modulatory Effect of Theaflavins on Apical Sodium-Dependent Bile Acid Transporter (ASBT) Activity.

Pub. Date : 2021 Aug 25

PMID : 34346218






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ASBT is responsible for most of the taurocholic acid (TC) uptake in Caco-2 cells. Taurocholic Acid solute carrier family 10 member 2 Homo sapiens
2 ASBT is responsible for most of the taurocholic acid (TC) uptake in Caco-2 cells. Taurocholic Acid solute carrier family 10 member 2 Homo sapiens
3 The results from the TC uptake assay using N-acetylcysteine suggested that the inhibitory effect of TF2A and TF2B was attributed to the oxidization of their benzotropolone rings and their covalent bonding with ASBT"s cysteine. Taurocholic Acid solute carrier family 10 member 2 Homo sapiens
4 TC uptake was reduced in the COS-7 cells expressing recombinant ASBT whose cysteine residues were mutated to alanine. Taurocholic Acid solute carrier family 10 member 2 Homo sapiens