Title : Pinocembrin pretreatment counteracts the chlorpyrifos-induced HO-1 downregulation, mitochondrial dysfunction, and inflammation in the SH-SY5Y cells.

Pub. Date : 2021 Dec

PMID : 34338973






3 Functional Relationships(s)
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Protein Name
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1 Pinocembrin pretreatment counteracts the chlorpyrifos-induced HO-1 downregulation, mitochondrial dysfunction, and inflammation in the SH-SY5Y cells. pinocembrin heme oxygenase 1 Homo sapiens
2 Silencing of Nrf2 or inhibition of HO-1 suppressed the PB-induced effects in the CPF-challenged cells. pinocembrin heme oxygenase 1 Homo sapiens
3 Thus, PB promoted beneficial effects by a mechanism dependent on the Nrf2/HO-1/CO + BR axis in the CPF-treated cells. pinocembrin heme oxygenase 1 Homo sapiens