Title : An inducible Cldn11-CreERT2 mouse line for selective targeting of lymphatic valves.

Pub. Date : 2021 Aug

PMID : 34338433






2 Functional Relationships(s)
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1 Here, we report on the generation of a transgenic mouse expressing the tamoxifen inducible CreERT2 under the control of Cldn11 promoter that allows, for the first time, selective and temporally controlled targeting of lymphatic valve endothelial cells. Tamoxifen mitogen-activated protein kinase 3 Mus musculus
2 Tamoxifen treated Cldn11-CreERT2 mice also carrying a fluorescent Cre-reporter displayed reporter protein expression selectively in lymphatic valves and, to a lower degree, in venous valves. Tamoxifen mitogen-activated protein kinase 3 Mus musculus