Title : Heterologous Expression and Auto-Activation of Human Pro-Inflammatory Caspase-1 in Saccharomyces cerevisiae and Comparison to Caspase-8.

Pub. Date : 2021

PMID : 34335569






1 Functional Relationships(s)
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1 Through the modulation of the GAL1 promoter by using different galactose:glucose ratios in the culture medium, we have established a scenario in which caspase-1 is sufficiently expressed to become activated while yeast growth is not impaired. Galactose galactokinase Saccharomyces cerevisiae S288C