Title : Statins act as transient type I interferon inhibitors to enable the antitumor activity of modified vaccinia Ankara viral vectors.

Pub. Date : 2021 Jul

PMID : 34321273






1 Functional Relationships(s)
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1 Simvastatin and atorvastatin efficiently abrogated for 8 hours the transcriptomic response to IFNalpha and enhanced the number of dendritic cells presenting an OVA-derived peptide bound to major histocompatibility complex (MHC) class I. Atorvastatin interferon alpha 1 Homo sapiens