Title : Effect of resveratrol on inflammatory cytokines: A meta-analysis of randomized controlled trials.

Pub. Date : 2021 Oct 5

PMID : 34303665






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1 The aim of the current study was to perform a meta-analysis of randomized clinical trials regarding the effect of resveratrol in decreasing the levels of inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8, and tumor necrosis factor (TNF)-alpha in a combination of inflammatory diseases. Resveratrol interleukin 6 Homo sapiens
2 A significant reduction of IL-6 concentration was observed only in the patients receiving >=500 mg/day dose of resveratrol (WMD = -1.89 pg/ml, 95% CI = -3.73 to -0.05, P = 0.04) with inter-study heterogeneity (I2 = 94.4%, P < 0.001). Resveratrol interleukin 6 Homo sapiens
3 Based on the present findings, resveratrol is able to decrease TNF-alpha and IL-6 (in >=500 mg/day dose) levels but not IL-1 and IL-8 levels. Resveratrol interleukin 6 Homo sapiens