Title : Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages.

Pub. Date : 2021

PMID : 34295923






2 Functional Relationships(s)
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1 Consequently, the cellular levels of prostaglandin E2 (PGE2) was also decreased, indicating that NMN inactivated macrophages via COX-2-PGE2 pathway, which was validated in activated THP-1 cells and mouse peritoneal macrophages. Dinoprostone prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Consequently, the cellular levels of prostaglandin E2 (PGE2) was also decreased, indicating that NMN inactivated macrophages via COX-2-PGE2 pathway, which was validated in activated THP-1 cells and mouse peritoneal macrophages. Dinoprostone prostaglandin-endoperoxide synthase 2 Homo sapiens