Title : Clinical Observation of Gene Polymorphism of Olanzapine or Aprepitant in Prevention of CINV.

Pub. Date : 2021

PMID : 34290520






1 Functional Relationships(s)
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1 Objective: The present study aims to investigate the correlation between the gene polymorphisms of the multidrug resistance protein 1 (ABCB1), the intron region of transcriptional factor (GTF2E1) and catechol-O-methyltransferase (COMT), dopamine receptor (DRD2), and the control of chemotherapy-induced nausea and vomiting (CINV) by olanzapine or aprepitant in a Chinese population under a fractionated cisplatin dosing pattern. Cisplatin ATP binding cassette subfamily B member 1 Homo sapiens