Title : Hydrogen peroxide induces progranulin expression to control neurite outgrowth in HT22 cells.

Pub. Date : 2021 Sep 22

PMID : 34289035






7 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Hydrogen peroxide induces progranulin expression to control neurite outgrowth in HT22 cells. Hydrogen Peroxide granulin Mus musculus
2 We observed that p38 MAP kinase was activated upon the addition of H2O2, and a selective p38 MAP kinase inhibitor, attenuated PGRN induction by H2O2. Hydrogen Peroxide granulin Mus musculus
3 We observed that p38 MAP kinase was activated upon the addition of H2O2, and a selective p38 MAP kinase inhibitor, attenuated PGRN induction by H2O2. Hydrogen Peroxide granulin Mus musculus
4 To explore the physiological role(s) of the PGRN induction, we first confirmed H2O2-dependent responses of HT22 cells and found that the length and number of neurites were increased by H2O2. Hydrogen Peroxide granulin Mus musculus
5 To explore the physiological role(s) of the PGRN induction, we first confirmed H2O2-dependent responses of HT22 cells and found that the length and number of neurites were increased by H2O2. Hydrogen Peroxide granulin Mus musculus
6 Pgrn knockdown experiments suggested these changes were mediated by H2O2-induced PGRN expression, at least in part. Hydrogen Peroxide granulin Mus musculus
7 Pgrn knockdown experiments suggested these changes were mediated by H2O2-induced PGRN expression, at least in part. Hydrogen Peroxide granulin Mus musculus