Title : Depression accelerates gastric cancer invasion and metastasis by inducing a neuroendocrine phenotype via the catecholamine/β2 -AR/MACC1 axis.

Pub. Date : 2021 Oct

PMID : 34288568






1 Functional Relationships(s)
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1 Further, depression-associated catecholamine specifically bound to the beta-2 adrenergic receptor (beta2 -AR) and upregulated MACC1 expression, and thus promoting neuroendocrine phenotypic transformation through direct binding between MACC1 and synaptophysin. Catecholamines adrenoceptor beta 2 Homo sapiens