Title : Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.

Pub. Date : 2021 Oct

PMID : 34284287






1 Functional Relationships(s)
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1 We found IGU decreased pulmonary inflammation and fibrosis and expression of fibrosis-related genes such as Collagen I, alpha-smooth muscle actin (alpha-SMA) and matrix metalloproteinase-2 (MMP-2) induced by bleomycin. Bleomycin actin alpha 2, smooth muscle, aorta Mus musculus