Pub. Date : 2021 Aug
PMID : 34281834
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MATERIALS AND METHODS: Parental human CRPC cell line PC3 (PC3/P) was continuously exposed to increasing doses of docetaxel, and a cell line resistant to docetaxel, PC3/R, was developed. | Docetaxel | proprotein convertase subtilisin/kexin type 1 | Homo sapiens |
| 2 | MATERIALS AND METHODS: Parental human CRPC cell line PC3 (PC3/P) was continuously exposed to increasing doses of docetaxel, and a cell line resistant to docetaxel, PC3/R, was developed. | Docetaxel | proprotein convertase subtilisin/kexin type 1 | Homo sapiens |
| 3 | MATERIALS AND METHODS: Parental human CRPC cell line PC3 (PC3/P) was continuously exposed to increasing doses of docetaxel, and a cell line resistant to docetaxel, PC3/R, was developed. | Docetaxel | proprotein convertase subtilisin/kexin type 1 | Homo sapiens |
| 4 | Furthermore, additional treatment of PC3/R with a specific inhibitor of AKT significantly enhanced the cytotoxic activity of docetaxel but not that of cabazitaxel. | Docetaxel | proprotein convertase subtilisin/kexin type 1 | Homo sapiens |