Title : Identification of the calpain-generated toxic fragment of ataxin-3 protein provides new avenues for therapy of Machado-Joseph disease| Spinocerebellar ataxia type 3.

Pub. Date : 2022 Feb

PMID : 34273111






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Expansion of a CAG trinucleotide in the MJD1 gene translates into a polyglutamine tract within ataxin-3, which upon proteolysis may lead to MJD. polyglutamine ataxin 3 Mus musculus
2 Expansion of a CAG trinucleotide in the MJD1 gene translates into a polyglutamine tract within ataxin-3, which upon proteolysis may lead to MJD. polyglutamine ataxin 3 Mus musculus