Title : Regioselective progesterone hydroxylation catalyzed by eleven rat hepatic cytochrome P-450 isozymes.

Pub. Date : 1987 Nov 3

PMID : 3427059






1 Functional Relationships(s)
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1 Results of microsomal metabolism in conjunction with antibody inhibition experiments indicated that cytochromes P-450a and P-450h were the sole 7 alpha- and 2 alpha-hydroxylases, respectively, and that P-450k or an immunochemically related isozyme contributed greater than 80% of the 21-hydroxylase activity observed in microsomes from phenobarbital-induced rats. Phenobarbital cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus