Title : β-Elemene Triggers ROS-dependent Apoptosis in Glioblastoma Cells Through Suppressing STAT3 Signaling Pathway.

Pub. Date : 2021

PMID : 34257541






3 Functional Relationships(s)
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1 beta-Elemene Triggers ROS-dependent Apoptosis in Glioblastoma Cells Through Suppressing STAT3 Signaling Pathway. beta-elemene signal transducer and activator of transcription 3 Homo sapiens
2 Western blot assay showed that beta-elemene suppressed phosphorylation of STAT3, and subsequently down-regulated the activation of p-JAK2 and p-Src. beta-elemene signal transducer and activator of transcription 3 Homo sapiens
3 Overall, our findings implied that generation of ROS and suppression of STAT3 signaling pathway is critical for the apoptotic activity of beta-elemene in glioblastoma cells. beta-elemene signal transducer and activator of transcription 3 Homo sapiens