Pub. Date : 2021
PMID : 34257541
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | beta-Elemene Triggers ROS-dependent Apoptosis in Glioblastoma Cells Through Suppressing STAT3 Signaling Pathway. | beta-elemene | signal transducer and activator of transcription 3 | Homo sapiens |
2 | Western blot assay showed that beta-elemene suppressed phosphorylation of STAT3, and subsequently down-regulated the activation of p-JAK2 and p-Src. | beta-elemene | signal transducer and activator of transcription 3 | Homo sapiens |
3 | Overall, our findings implied that generation of ROS and suppression of STAT3 signaling pathway is critical for the apoptotic activity of beta-elemene in glioblastoma cells. | beta-elemene | signal transducer and activator of transcription 3 | Homo sapiens |