Pub. Date : 2021 Sep 1
PMID : 34242566
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Benzo(a)pyrene (BaP) is a strong carcinogen for lung cancer, and forkhead-box A1 (FOXA1) plays an oncogenic role in BaP-transformed cell THBEc1. | Benzo(a)pyrene | forkhead box A1 | Homo sapiens |
| 2 | Benzo(a)pyrene (BaP) is a strong carcinogen for lung cancer, and forkhead-box A1 (FOXA1) plays an oncogenic role in BaP-transformed cell THBEc1. | Benzo(a)pyrene | forkhead box A1 | Homo sapiens |
| 3 | Benzo(a)pyrene (BaP) is a strong carcinogen for lung cancer, and forkhead-box A1 (FOXA1) plays an oncogenic role in BaP-transformed cell THBEc1. | Benzo(a)pyrene | forkhead box A1 | Homo sapiens |
| 4 | To explore the remodeling of metabolic pattern caused by BaP-induced transformation and the possible role FOXA1 might play in it, we compared metabolic patterns between THBEc1 cells and control using untargeted metabolomics and lipidomics analysis, and determined the effects of FOXA1 knockout on the metabolic pattern of THBEc1 cells. | Benzo(a)pyrene | forkhead box A1 | Homo sapiens |
| 5 | In conclusion, FOXA1 knockout partially reversed the remodeling of glucose metabolism caused by BaP-induced malignant transformation. | Benzo(a)pyrene | forkhead box A1 | Homo sapiens |