Title : Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial.

Pub. Date : 2021 Sep 1

PMID : 34236401






1 Functional Relationships(s)
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1 KIT inhibitors commonly used to treat GIST (eg, imatinib and sunitinib) are inactive-state (type II) inhibitors. Imatinib Mesylate KIT proto-oncogene, receptor tyrosine kinase Homo sapiens