Title : Capsaicin affects macrophage anti-inflammatory activity via the MAPK and NF-κB signaling pathways.

Pub. Date : 2021 Jul 8

PMID : 34235954






1 Functional Relationships(s)
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1 Overall, capsaicin reduced the secretion of inflammatory cytokines (P<0.01), interleukins, TNF-alpha (P<0.01), and NO by inhibiting the nuclear factor-kappa B and microtubule-associated protein kinase signaling pathways, and thereby reduced lipopolysaccharide-induced inflammatory response in macrophages. Capsaicin tumor necrosis factor Mus musculus