Title : The inhibition of catechol O-methyltransferase and monoamine oxidase by tetralone and indanone derivatives substituted with the nitrocatechol moiety.

Pub. Date : 2021 Sep

PMID : 34225162






1 Functional Relationships(s)
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1 COMT inhibitors enhance the bioavailability of levodopa to the brain, and therefore are combined with levodopa for the treatment of motor fluctuations in PD. Levodopa catechol-O-methyltransferase Homo sapiens