Title : Dietary 5-demethylnobiletin modulates xenobiotic-metabolizing enzymes and ameliorates colon carcinogenesis in benzo[a]pyrene-induced mice.

Pub. Date : 2021 Sep

PMID : 34216713






1 Functional Relationships(s)
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1 Our results showed that 5-DMNB had a substantial inhibitory effect on CYP1B1 induced by BaP and upregulated the detoxification enzymes UDP-glucuronosyltransferases (UGTs) and glutathione S-transferases (GSTs). Benzo(a)pyrene cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus