Title : Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport.

Pub. Date : 2021 Oct

PMID : 34212529






2 Functional Relationships(s)
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1 These findings were primarily explained by the ability of miconazole in altering the kinetic/efficacy of de-glucuronidation of the endogenous steroids by the enzyme beta-glucuronidase during the sample preparation process. Miconazole glucuronidase beta Homo sapiens
2 The increase of both incubation time and amount of beta-glucuronidase was demonstrated to be effective countermeasures in the presence of miconazole to reduce the risk of uncorrected interpretation of the results. Miconazole glucuronidase beta Homo sapiens