Pub. Date : 2021 Jun 30
PMID : 34209301
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ABCB4 (ATP-binding cassette subfamily B member 4) is an ABC transporter expressed at the canalicular membrane of hepatocytes where it ensures phosphatidylcholine secretion into bile. | Phosphatidylcholines | ATP binding cassette subfamily B member 4 | Homo sapiens |
| 2 | ABCB4 (ATP-binding cassette subfamily B member 4) is an ABC transporter expressed at the canalicular membrane of hepatocytes where it ensures phosphatidylcholine secretion into bile. | Phosphatidylcholines | ATP binding cassette subfamily B member 4 | Homo sapiens |
| 3 | Our results indicate that the overexpression of wild type RAB10 or its dominant-active mutant significantly increases the amount of ABCB4 at the plasma membrane expression and its phosphatidylcholine floppase function. | Phosphatidylcholines | ATP binding cassette subfamily B member 4 | Homo sapiens |
| 4 | Taken together, our findings suggest that RAB10 regulates the plasma membrane targeting of ABCB4 and consequently its capacity to mediate phosphatidylcholine secretion. | Phosphatidylcholines | ATP binding cassette subfamily B member 4 | Homo sapiens |