Pub. Date : 2021 Sep 1
PMID : 34190716
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | There was no statistically significant difference in ERK activation compared with placebo (P=0.45); however, ERK activation was reduced 74% compared with pretreatment biopsy with vandetinib treatment (P=0.005) without a significant reduction in the placebo group (-29%, P=0.55). | vandetanib | EPH receptor B2 | Homo sapiens |
| 2 | In accordance with the investigational hypothesis, there was a nonsignificant trend with vandetanib treatment of reduction in p-ERK and increased effects in Ret expressing tumors. | vandetanib | EPH receptor B2 | Homo sapiens |