Pub. Date : 2021 Jul 13
PMID : 34189538
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | T-cell mediated immunity after AZD1222 vaccination: A polyfunctional spike-specific Th1 response with a diverse TCR repertoire. | azd1222 | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 2 | Total spike-specific CD4+ T cell helper type 1 (Th1) and CD8+ T-cell responses were significantly increased in AZD1222-vaccinated adults of all ages following two doses of AZD1222. | azd1222 | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 3 | Total spike-specific CD4+ T cell helper type 1 (Th1) and CD8+ T-cell responses were significantly increased in AZD1222-vaccinated adults of all ages following two doses of AZD1222. | azd1222 | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 4 | T-cell receptor (TCR) beta sequences from vaccinated participants mapped against TCR sequences known to react to SARS-CoV-2 revealed substantial breadth and depth across the SARS-CoV-2 spike protein for the AZD1222-induced CD4+ and CD8+ T-cell responses. | azd1222 | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 5 | One Sentence Summary: Polyfunctional CD4+ and CD8+ T-cell responses are elicited against the SARS-CoV-2 spike protein following vaccination with AZD1222. | azd1222 | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |