Title : Serum albumin modified by carbamoylation impairs macrophage cholesterol efflux in diabetic kidney disease.

Pub. Date : 2021 Sep

PMID : 34183248






2 Functional Relationships(s)
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1 There was reduction in the 14C-cholesterol efflux after treatment for 18h with albumin isolated from patients with eGFR<60mL/min/1.73m2 compared with control group mediated by HDL2 (p=0.0288) and HDL3 (p<0.0001), as well as when compared with eGFR >=60mL/min/1.73m2 per HDL2 (p=0.0001) and HDL3 (p<0.0001). Carbon-14 junctophilin 3 Homo sapiens
2 Treatment for 48h showed that eGFR<15mL/min/1.73m2 had a lower percentage of 14C-cholesterol efflux mediated by HDL2 compared to control and other CKD groups (p=0.0274). Carbon-14 junctophilin 3 Homo sapiens