Title : HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F-actin signalling pathway.

Pub. Date : 2021 Aug

PMID : 34180140






2 Functional Relationships(s)
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1 Moreover, ACY1215 inhibited the level of NLRP3, ASC, caspase-1, IL-1beta and IL-18 in ALF. ricolinostat steroid sulfatase Mus musculus
2 Cytochalasin B could dramatically increase the level of NLRP3, ASC, caspase-1, IL-1beta and IL-18 in ALF with ACY1215 pretreatment. ricolinostat steroid sulfatase Mus musculus