Title : Therapeutic targets and molecular mechanism of calycosin for the treatment of cerebral ischemia/reperfusion injury.

Pub. Date : 2021 Jun 27

PMID : 34176787






2 Functional Relationships(s)
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1 Molecular docking analysis indicated the binding efficacy of calycosin with three of the targets, namely TP53, AKT1, and VEGFA. 7,3'-dihydroxy-4'-methoxyisoflavone vascular endothelial growth factor A Homo sapiens
2 In addition, the anti-CIRI actions of calycosin were primarily through suppression of the toll-like receptor, PI3K-AKT, TNF, MAPK, and VEGF signaling pathways. 7,3'-dihydroxy-4'-methoxyisoflavone vascular endothelial growth factor A Homo sapiens